Paternal Family History Ignored While Assessing Breast Cancer-9c8836

Cancer STUDY SUGGESTS that father’s family history of breast cancer and ovarian cancer is generally overlooked by both patients and doctors. Genetic counselor Jeanna McCuaig and her co-authors from Toronto’s Princess Margaret Hospital in Toronto and Montreal wrote in commentary in the journal The Lancet Oncology, healthcare providers may be "unaware that these women might have inherited the mutated gene from their father and might not routinely collect this information from their patients." Women don’t recognize a paternal family history of cancer as a risk factor for the diseases, and are unlikely to volunteer the information unless directly questioned. Women and men both have 50 percent risk of passing on mutations in the BRCA1 or BRCA2 tumour suppressor genes, which increase lifetime risk for breast cancer and ovarian cancer. The researchers also determined patients were 5 times more likely to be referred with a paternal, than a maternal, family history of breast or ovarian cancer. A study, led by researchers at Memorial Sloan-Kettering Cancer Center, has suggested that genetic variants on chromosomes 10 and 20 may modify risk of breast cancer among women with a BRCA2 mutation. Researchers analysed DNA samples from 6,272 women with BRCA2 mutations in a two-stage genome-wide association study. The chromosome-10 variant identified in the study, near the gene ZNF365, decreased the risk of breast cancer by approximately 25 percent in women also carrying a mutation of the BRCA2 gene. Researchers suggested that healthcare providers should be familiar with general trends in genetic cancers, including: -Diagnosis at younger ages than sporadic cancers. -Several family members over generations might be diagnosed with cancer, particularly rare forms or breast cancer and ovarian cancer. -Diagnosis with many primary type of cancers. According to a study, about 20 to 30 per cent of the more than 6,90,000 women diagnosed with breast cancer and nearly 1,90,000 diagnosed with ovarian cancer in developed countries have had a family history of cancer. The BRCA1 and BRCA2 mutations are linked to aggressive hereditary breast cancers, but only account for about 15 percent of all cases. About the Author: By: Travel Care Air – An in depth look at a few of the top hospitals in the United States for cancer treatment. By: methuentailor000 – CyberKnife Medanta hospital delivers outreach treatment for the brain tumor and other cancer treatment in India followed by compassionate and personalized care to the patients. By: smartweb – Sydney is easily the biggest and most inhabited city in Australia. Sydney features a highly developed marketplace economy with strengths in manufacturing, finance, & tourism and therefore there is a continuous requirement to develop and put up its infrastructure. By: Hadiyah Aswad – Owning certification like IBM Cognos TM1 10.1 Developer is an amazing opportunity to possess success in the industry. By: Hadiyah Aswad – In order to practice and prepare for this examination, you will need to put money and effort both to receive the maximum benefit in the long run for your career path. By: Hadiyah Aswad – You will also get the authority of using the title of IBM Cognos Business Intelligence Sales Professional also the test shows compatibility with skills criterion which has been set for the SVI/SVP. By: Sandler-Kenner Foundation – Gaining a better understanding of pancreatic cancers risk factors was the focus of a recent study conducted at the Mayo Clinic in Jacksonville. By: Vanya – As it is known that there are many treatment methods available for lung cancer but homeopathy is one of the most effective and safest methods to treat lung cancer. Due to various advantages of Molecular homeopathic treatment method it is in much more practice than conventional treatment methods. T … By: Martin clark – There are many leading animation courses providing institutions available in India and they are offering many courses that enable use of many industries in the world. The courses will be categorized as web design, animation, VFX, broadcast, gaming, and multimedia. By: alexclark512 – Cancer pain is usually caused by the tumor pressing on bones, nerves or other organs in a body. Sometimes the pain is directly related to the treatment that is going on for the disease. For example, some chemotherapy drugs can cause numbness and tingling in hands and feet or a burning sensation at … 相关的主题文章: